Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469479 | 0.95 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL9470150 | 0.82 | LMNA (0.52) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL9470154 | 0.82 | LMNA (0.52) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL1549121 | 0.81 | USP2 (0.58) | ALDH1A1SMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL8158041 | 0.81 | PPARG (0.58) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL3956777 | 0.81 | PPARG (0.49) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL3956764 | 0.81 | PPARG (0.49) | CYP4F2CYP4A11ALDH1A1TDP1LTA4H | |
| SCHEMBL14298119 | 0.81 | L3MBTL1 (0.60) | CYP4F2CYP4A11ALDH1A1TDP1CYP1A2 | |
| SCHEMBL10745866 | 0.81 | ALDH1A1 (0.56) | CYP4F2CYP4A11ALDH1A1LTA4HSMN1; SMN2 | |
| SCHEMBL29213722 | 0.80 | TDP1 (0.64) | ALDH1A1TDP1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |