Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545870 | 0.87 | RAB9A (0.71) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL29799252 | 0.84 | LCK (0.58) | MAOAMAOBLCKALDH1A1KDM4E | |
| SCHEMBL8621941 | 0.82 | RAB9A (0.59) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL9469211 | 0.82 | RAB9A (0.59) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL27983208 | 0.81 | RAB9A (0.63) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL3083923 | 0.81 | MAOA (0.81) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL3423658 | 0.80 | MAOB (0.65) | RAB9AMAOAMAOB | |
| SCHEMBL2019824 | 0.80 | MAOB (0.76) | RAB9AMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL1164139 | 0.80 | MAOB (0.74) | RAB9AMAOAMAOBNPC1TDP1 | |
| SCHEMBL13220846 | 0.80 | MAOB (0.76) | RAB9AMAOAMAOBNPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219710-A | Optical waveguides; change refractive index upon exposure to actinic radiation; heat resistant | ALLIED-SIGNAL INC. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1993011169-A1 | POLYMERIC NITRONES HAVING A STYRENE-DERIVED BACKBONE CHAIN | ALLIED-SIGNAL INC. (US) | 1993-06-10 | — | — | WO | disclosed |