SCHEMBL9469629

SCHEMBL9469629

C=CCOc1ccc(-c2ccccc2C#N)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.50
ESR2 Q92731 1/20 0.50
AKR1B1 P15121 1/20 0.50
SQOR Q9Y6N5 1/20 0.41
PTPN5 P54829 1/20 0.40
BACE1 P56817 1/20 0.40
PTPN1 P18031 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469373 0.84 SLC6A2 (0.48) FFAR1ESR2MAOAMAOBALDH1A1
SCHEMBL9478721 0.81 ESR2 (0.49) FFAR1ESR2AKR1B1PTPN5MAOA
SCHEMBL6957583 0.81 ESR2 (0.56) FFAR1ESR2AKR1B1PTPN5PTPN1
SCHEMBL6960961 0.80 ESR2 (0.54) FFAR1ESR2AKR1B1PTPN5PTPN1
SCHEMBL2395315 0.78 HPGD (0.43) ESR2SQORKDM4EALDH1A1MAPK1
SCHEMBL11314486 0.78 PTPRC (0.39) FFAR1ESR2AKR1B1SQORMAOA
SCHEMBL19921086 0.78 ADRB2 (0.48) CA12CA1CA2CA7CA9
SCHEMBL30255107 0.77 PTGDR2 (0.47) SQORBACE1MAOBMAPTADORA3
SCHEMBL2356935 0.77 MMP2 (0.50) MAOBCA12CA1CA2CA7
SCHEMBL7836773 0.77 FFAR1 (0.72) FFAR1ESR2AKR1B1PTPN1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5262052-A Separation of polycyclic aromatic hydrocarbons BRIGHAM YOUNG UNIVERSITY (US) 1993-11-16 US disclosed