Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590769 | 0.80 | USP2 (0.42) | MAPTLMNAUSP2 | |
| SCHEMBL10593128 | 0.80 | USP2 (0.42) | MAPTLMNAUSP2 | |
| SCHEMBL10594537 | 0.80 | USP2 (0.42) | MAPTLMNAUSP2 | |
| SCHEMBL10698885 | 0.79 | CES2 (0.41) | PRKCAFAAHCES2LMNATSHR | |
| SCHEMBL9837662 | 0.79 | TSHR (0.42) | PRKCACES2LMNATSHR | |
| SCHEMBL8103942 | 0.78 | CES2 (0.46) | PRKCAFAAHCES2LMNATSHR | |
| SCHEMBL5192045 | 0.78 | CES2 (0.46) | PRKCAFAAHCES2LMNATSHR | |
| SCHEMBL9007930 | 0.76 | TRPV1 (0.50) | PRKCAFAAHMAPTMAPK1LMNA | |
| SCHEMBL27969815 | 0.75 | ALDH1A1 (0.48) | PRKCAFAAHMAPTCES2LMNA | |
| SCHEMBL12671785 | 0.75 | TSHR (0.38) | LMNATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284395-B1 | NOVEL GLYCEROL DERIVATIVE AND ANTI-HYPERTENSIVE AGENT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-5183811-A | Glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| US-4962096-A | WITH REDUCED PLATELET AGGREGATING ACTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |