Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837662 | 0.80 | TSHR (0.42) | CES2LMNATSHRPRKCANAAA | |
| SCHEMBL8103942 | 0.79 | CES2 (0.46) | CES2LMNATSHRPRKCANAAA | |
| SCHEMBL5192045 | 0.79 | CES2 (0.46) | CES2LMNATSHRPRKCANAAA | |
| SCHEMBL9469680 | 0.79 | PRKCA (0.43) | CES2LMNATSHRPRKCAFAAH | |
| SCHEMBL27969815 | 0.77 | ALDH1A1 (0.48) | CES2LMNATSHRPRKCAALDH1A1 | |
| SCHEMBL12154402 | 0.75 | ALDH1A1 (0.52) | CES2LMNATSHRPRKCANAAA | |
| SCHEMBL10591201 | 0.75 | HCAR2 (0.41) | CES2TSHRNAAADNM1HCAR2 | |
| SCHEMBL10590620 | 0.75 | HCAR2 (0.41) | CES2TSHRNAAADNM1HCAR2 | |
| SCHEMBL10593296 | 0.75 | HCAR2 (0.41) | CES2TSHRNAAADNM1HCAR2 | |
| SCHEMBL10592752 | 0.75 | HCAR2 (0.41) | CES2TSHRNAAADNM1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |