Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 2/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708579 | 0.74 | DDB1 (0.53) | DDB1CRBNKMT2ACFTRGOPC | |
| SCHEMBL978197 | 0.69 | PTGS2 (0.68) | KMT2ACFTRGOPCPTGS1PTGS2 | |
| SCHEMBL13210441 | 0.69 | DDB1 (0.57) | DDB1CRBNKMT2ACFTRGOPC | |
| SCHEMBL15874625 | 0.68 | CYP19A1 (0.76) | DDB1CRBNCYP19A1LMNA | |
| SCHEMBL20585273 | 0.68 | CYP19A1 (0.76) | DDB1CRBNCYP19A1LMNA | |
| SCHEMBL15292027 | 0.68 | CYP19A1 (0.76) | DDB1CRBNCYP19A1LMNA | |
| SCHEMBL976923 | 0.68 | DDB1 (0.47) | DDB1CRBNKMT2ACFTRGOPC | |
| SCHEMBL4810645 | 0.68 | CYP19A1 (0.76) | DDB1CRBNCYP19A1LMNA | |
| SCHEMBL17163859 | 0.68 | CFTR (0.41) | KMT2ACFTRGOPCPTGS1PDGFRA | |
| SCHEMBL14880674 | 0.67 | DDB1 (0.46) | DDB1CRBNCFTRGOPCCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243016-A | Improved solubility, polyimides, polyether ketones, polyesters, polyether sulfones | HAY ALLAN S (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5182358-A | Polyetherketones, polyethersulfone, polyetherimides, solubility in organic solvents | HAY ALLAN S (CA) | 1993-01-26 | — | — | US | disclosed |