Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470320 | 0.82 | SLC18A3 (0.34) | ALDH1A1LMNAPOLB | |
| SCHEMBL9469702 | 0.80 | POLB (0.48) | ALDH1A1LMNAPOLB | |
| SCHEMBL9470368 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLB | |
| SCHEMBL9469636 | 0.70 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL9470596 | 0.70 | TP53 (0.40) | ALDH1A1LMNA | |
| SCHEMBL9470115 | 0.70 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL9470178 | 0.69 | MAOA (0.41) | ALDH1A1LMNAPOLB | |
| SCHEMBL9470503 | 0.68 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLB | |
| SCHEMBL9470196 | 0.68 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL20067119 | 0.67 | PSEN1 (0.39) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182289-A | Pyrrolo 2,3-b!Pyridin-2-one Derivatives | SCHERING CORPORATION (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0419561-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1989012637-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |