Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469385 | 0.95 | GAA (0.39) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL9470368 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL9469283 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL4690229 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL9470115 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDGAAL3MBTL1 | |
| SCHEMBL9470196 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDGAAL3MBTL1 | |
| SCHEMBL9470300 | 0.82 | MAPT (0.39) | ALDH1A1MAPTGAALMNAMEN1 | |
| SCHEMBL9470466 | 0.82 | KMT2A (0.47) | ALDH1A1MAPTHPGDGAAL3MBTL1 | |
| SCHEMBL9469636 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDGAAL3MBTL1 | |
| SCHEMBL9469535 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182289-A | Pyrrolo 2,3-b!Pyridin-2-one Derivatives | SCHERING CORPORATION (US) | 1993-01-26 | — | — | US | claimed |
| EP-0419561-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1991-04-03 | — | — | EP | claimed |
| WO-1989012637-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1989-12-28 | — | — | WO | claimed |
| EP-0347698-A1 | Heterobicyclic compounds having antiinflammatory activity | SCHERING CORPORATION (US) | 1989-12-27 | — | — | EP | claimed |
| EP-0419561-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1991-04-03 | — | — | EP | disclosed |
| WO-1989012637-A1 | HETEROBICYCLIC COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY | SCHERING CORPORATION (US) | 1989-12-28 | — | — | WO | disclosed |