Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13495086 | 1.00 | CHRNB2 (0.48) | CHRNB2CHRNA4HTR3ACHRNA7LSS | |
| Hydrochloric Acid SCHEMBL8988229 | 0.85 | CHRNB2 (0.50) | CHRNB2CHRNA4HTR3ACHRNA7LSS | |
| SCHEMBL13495085 | 0.85 | ALDH1A1 (0.55) | CHRNA7LSSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6941982 | 0.84 | LSS (0.57) | CHRNA7LSS | |
| SCHEMBL5407244 | 0.84 | CHRM2 (0.45) | CHRNA7LSS | |
| Hydrochloric Acid SCHEMBL5651736 | 0.82 | CHRM2 (0.44) | CHRNA7LSS | |
| SCHEMBL1848679 | 0.82 | CHRM2 (0.47) | CHRNA7LSSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1849637 | 0.82 | CHRM2 (0.47) | CHRNA7LSSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13495092 | 0.82 | LSS (0.46) | CHRNA7LSSSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3238906 | 0.82 | LSS (0.49) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258392-A | 3-quinuclidine derivatives | AKZO N.V. (NL) | 1993-11-02 | — | — | US | disclosed |
| EP-0497415-A1 | 3-Quinuclidine derivatives | Akzo Nobel N.V. (NL) | 1992-08-05 | — | — | EP | disclosed |