SCHEMBL6941982

SCHEMBL6941982

COc1ccc(OC2CN3CCC2CC3)cc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.57
CHRNA7 P36544 1/20 0.53
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1019927 0.92 LSS (0.51) LSSCHRNA7CHRM2CHRM1
SCHEMBL3229552 0.86 CHRNA7 (0.68) LSSCHRNA7CHRM1
SCHEMBL3229549 0.86 CHRNA7 (0.68) LSSCHRNA7CHRM1
SCHEMBL5390772 0.86 LSS (0.60) LSSCHRNA7
SCHEMBL13495086 0.84 CHRNB2 (0.48) LSSCHRNA7
SCHEMBL9469879 0.84 CHRNB2 (0.48) LSSCHRNA7
SCHEMBL1849257 0.83 LSS (0.57) LSSCHRNA7CHRM2CHRM4CHRM5
SCHEMBL2323165 0.83 LSS (0.57) LSSCHRNA7
SCHEMBL3215152 0.83 LSS (0.78) LSSCHRNA7
SCHEMBL3215158 0.83 LSS (0.78) LSSCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030138376-A1 Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form H. LUNDBECK A/S (DK) 2003-07-24 US disclosed
EP-1268051-A2 DOSING FORM FOR REAGENTS, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND PRODUCTION OF SAID DOSING FORM H. Lundbeck A/S (DK) 2003-01-02 EP disclosed
WO-2001068599-A2 DOSING FORM FOR REAGENTS, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND PRODUCTION OF SAID DOSING FORM H. LUNDBECK A/S (DK) 2001-09-20 WO disclosed
US-5258392-A 3-quinuclidine derivatives AKZO N.V. (NL) 1993-11-02 US disclosed
EP-0497415-A1 3-Quinuclidine derivatives Akzo Nobel N.V. (NL) 1992-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030138376-A1 Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form ATIC, SET, SORD LSS 643/4885CHRNA7 4549/4885CHRM2 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.