⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269873 | 0.98 | LMNA (0.31) | — | |
| SCHEMBL2927401 | 0.93 | LMNA (0.31) | — | |
| SCHEMBL13602993 | 0.89 | LMNA (0.32) | — | |
| SCHEMBL10753254 | 0.89 | ODC1 (0.32) | — | |
| SCHEMBL303927 | 0.86 | ODC1 (0.33) | — | |
| SCHEMBL11359500 | 0.86 | LMNA (0.33) | — | |
| SCHEMBL20090051 | 0.83 | — | — | |
| SCHEMBL10753439 | 0.82 | NFKB1 (0.33) | — | |
| SCHEMBL12995304 | 0.81 | LMNA (0.38) | — | |
| SCHEMBL9491840 | 0.81 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248760-A | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | UNC AT CHARLOTTE (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992013024-A1 | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 1992-08-06 | — | — | WO | claimed |
| US-5248760-A | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | UNC AT CHARLOTTE (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1992013024-A1 | CHEMICALLY CURED LOW TEMPERATURE POLYIMIDES | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 1992-08-06 | — | — | WO | disclosed |