SCHEMBL9470534

SCHEMBL9470534

NC(=O)Cc1ccc(C(=O)O)c(O)c1.[PbH2]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 5/20 0.52
MAPT P10636 3/20 0.52
GAA P10253 2/20 0.52
ESR2 Q92731 2/20 0.52
CYP3A4 P08684 1/20 0.52
PTPN1 P18031 1/20 0.52
PPARA Q07869 1/20 0.51
CA2 P00918 2/20 0.50
TSHR P16473 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
HPGD P15428 4/20 0.47
HSD17B10 Q99714 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
POLB P06746 2/20 0.47
RGS12 O14924 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13209792 0.98 ALDH1A1 (0.53) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL14879765 0.83 GAA (0.68) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL28115877 0.80 PPARA (0.57) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL702567 0.79 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL2734611 0.79 KDM4E (0.67) ALDH1A1KDM4EMAPTGAACYP3A4
Hydrochloric Acid SCHEMBL6289406 0.78 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL1401513 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL2837159 0.77 ALDH1A1 (0.57) ALDH1A1KDM4EMAPTGAAESR2
SCHEMBL15388380 0.77 CA2 (0.53) ALDH1A1MAPTGAAESR2CA2
SCHEMBL2777865 0.76 ALDH1A1 (0.70) ALDH1A1KDM4EMAPTGAACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5205983-A Mixture of sorbitol polynitrates and polyolpolynitrates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-04-27 US disclosed