Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470613 | 0.81 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3CHRNA7 | |
| SCHEMBL9469882 | 0.81 | LGALS9 (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL10240925 | 0.78 | CHRM2 (0.44) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL2621370 | 0.78 | SLC5A1 (0.50) | RAB9AKDM4ENPC1CHRM2CHRM4 | |
| SCHEMBL12069028 | 0.74 | LGALS9 (0.45) | CHRM2CHRM4CHRM1CHRM3CHRNA7 | |
| SCHEMBL15215812 | 0.74 | LGALS9 (0.45) | CHRM2CHRM4CHRM1CHRM3CHRNA7 | |
| SCHEMBL802486 | 0.72 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3CHRNA7 | |
| SCHEMBL10959939 | 0.72 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11611279 | 0.72 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 | |
| SCHEMBL11612977 | 0.72 | RAB9A (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |