Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9470841

Cc1ccc(S(=O)(=O)OCc2ccccc2)cc1.N

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
LMNA P02545 2/20 0.51
CYP1A2 P05177 2/20 0.50
CYP3A4 P08684 2/20 0.50
AR P10275 1/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
CA12 O43570 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 2/20 0.48
MCHR1 Q99705 1/20 0.47
PIR O00625 1/20 0.46
VDR P11473 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CNR2 P34972 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890 0.98 CA9 (0.53) CA9CA1CA2LMNACYP1A2
Toluene SCHEMBL9257721 0.97 CA9 (0.51) CA9CA1CA2LMNACYP1A2
N,N-Dimethylethanaminium SCHEMBL11574804 0.89 LMNA (0.46) CA9CA1CA2LMNACYP1A2
SCHEMBL6859827 0.89 CA2 (0.63) CA9CA1CA2CYP3A4BCHE
SCHEMBL8052920 0.89 CA2 (0.63) CA9CA1CA2CYP3A4BCHE
Glycine SCHEMBL6795033 0.88 LMNA (0.51) CA9CA1CA2LMNACYP1A2
SCHEMBL27966350 0.87 MAPT (0.48) CA9CA1CA2LMNACYP1A2
SCHEMBL4947525 0.86 CYP19A1 (0.53) CA9CA1CA2LMNACYP1A2
D-Alanine SCHEMBL21580302 0.85 LMNA (0.49) CA9CA1CA2LMNACYP1A2
Alanine SCHEMBL21580304 0.85 LMNA (0.49) CA9CA1CA2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117120445-A Process for the preparation of isohexide diamines from isohexide diols 科思创德国股份有限公司 2023-11-24 CN disclosed
US-5198320-A Polymers with oxygen linkages polysiloxanes EASTMAN KODAK COMPANY (US) 1993-03-30 US disclosed