Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Alanine SCHEMBL28276772 | 0.92 | LMNA (0.52) | LMNAMAPTCA1CA2CA9 | |
| SCHEMBL2890 | 0.89 | CA9 (0.53) | LMNAMAPTCA1CA2CA9 | |
| Ammonia Solution, Strong SCHEMBL9470841 | 0.88 | CA9 (0.51) | LMNAMAPTCA1CA2CA9 | |
| Toluene SCHEMBL9257721 | 0.88 | CA9 (0.51) | LMNAMAPTCA1CA2CA9 | |
| Alanine SCHEMBL27541536 | 0.86 | LMNA (0.49) | LMNAMAPTCA1CA2CA9 | |
| D-Alanine SCHEMBL21580302 | 0.86 | LMNA (0.49) | LMNAMAPTCA1CA2CA9 | |
| Alanine SCHEMBL21580304 | 0.86 | LMNA (0.49) | LMNAMAPTCA1CA2CA9 | |
| SCHEMBL16213019 | 0.85 | LMNA (0.48) | LMNAMAPTCA1CA2CA9 | |
| 1-Aminocyclopropane Carboxylic Acid SCHEMBL27560063 | 0.84 | LMNA (0.47) | LMNAMAPTCA1CA2CA9 | |
| Phenylalanine SCHEMBL7396105 | 0.83 | SLC7A5 (0.55) | LMNAMAPTCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119368011-A | Polyamide composite film | 万华化学集团股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-222263523-U | Perovskite solar cell | 旗滨新能源发展(深圳)有限责任公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-115968113-A | Method for manufacturing structure with conductive pattern, kit and system | 旭化成株式会社 | 2023-04-14 | — | — | CN | disclosed |
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | KYOWA KIRIN CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| EP-3888663-A1 | NUCLEIC ACID COMPLEX | Kyowa Kirin Co., Ltd. (JP) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021027306-A1 | DIHYDROARTEMISININ-STEROID CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 云白药征武科技(上海)有限公司 | 2021-02-18 | — | — | WO | disclosed |
| EP-3409780-B1 | NUCLEIC ACID COMPLEX | KYOWA KIRIN CO LTD (JP) | 2021-01-20 | — | — | EP | disclosed |
| US-10745700-B2 | Nucleic acid conjugate | KYOWA KIRIN CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| CN-110678174-A | Prodrugs of treprostinil | 联合治疗学有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20190055558-A1 | NUCLEIC ACID CONJUGATE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-02-21 | — | — | US | disclosed |
| EP-3409780-A1 | NUCLEIC ACID COMPLEX | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-6835851-B2 | Reacting said alpha - substituted acrylic acid with an chloro acid so as to obtain an acid chloride, now reacting acid chloride thus obtained with an amino ester in presence of an organic base, to acheive coupling | BIOPROJET (FR) | 2004-12-28 | — | — | US | disclosed |
| CN-1165336-C | Peptide, a method of obtaining it and a pharmaceutical compound based on it | ��ķ����ŵ | 2004-09-08 | — | — | CN | disclosed |
| US-20020055645-A1 | Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids | BIOPROJET (FR) | 2002-05-09 | — | — | US | disclosed |
| CN-1159758-A | Peptides, methods for obtaining and derivatizing peptides and pharmaceutical compositions based on derivatised peptides | V I DEIGIN (RU) | 1997-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | NSUN3, NSUN2, RNASEH1 | LMNA 1097/4885MAPT 3449/4885CA1 827/4885 |
| US-10745700-B2 | Nucleic acid conjugate | SLC29A1, NSUN2, H1-2 | LMNA 601/4885MAPT 2840/4885CA1 607/4885 |
| US-20020055645-A1 | Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids | TST, ASS1, SULT1A1 | LMNA 4652/4885MAPT 4554/4885CA1 2414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.