Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636314 | 0.89 | ALDH1A1 (0.52) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL6006737 | 0.89 | ALDH1A1 (0.52) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL27844440 | 0.89 | HTR6 (0.54) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL18401344 | 0.88 | HTR6 (0.54) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL5051390 | 0.87 | HTR6 (0.93) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL4982378 | 0.84 | HTR6 (0.88) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL29473549 | 0.84 | HTR6 (1.00) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.84 | HTR6 (1.00) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL29450723 | 0.84 | HTR6 (1.00) | HTR6ALDH1A1SMN1; SMN2POLBMAPT | |
| (Phenylsulfonyl)Benzene SCHEMBL29775288 | 0.84 | HTR6 (1.00) | HTR6ALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3692995-A1 | DEOXYCHOLATE FOR REDUCTION OF FAT | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2380576-B1 | Use of sodium deoxycholate for the non-surgical removal of fat | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2020-04-08 | — | — | EP | disclosed |
| CN-105073822-A | Epoxy resin composition and cured product thereof, prepreg, and fiber-reinforced composite material | DAICEL CORP | 2015-11-18 | — | — | CN | disclosed |
| EP-2572718-A1 | Methods and related compositions for reduction of fat | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2380576-A2 | Methods and related compositions for reduction of fat | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2011-10-26 | — | — | EP | disclosed |
| EP-1748780-B1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT | LOS ANGELES BIOMED RES INST (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20110002896-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT | REGENTS OF THE UNIVERSITY OF CALIFORINIA, THE LOS ANGELES BIOMEDICAL | 2011-01-06 | — | — | US | disclosed |
| US-20090012134-A1 | Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists | CURTIS NEIL ROY | 2009-01-08 | — | — | US | disclosed |
| EP-1866300-A1 | ARYLSULFONYL BENZOFUSED HETEROCYCLES AS 5-HT2A ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2007-12-19 | — | — | EP | disclosed |
| EP-1748780-A1 | METHODS AND RELATED COMPOSITIONS FOR REDUCTION OF FAT | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2007-02-07 | — | — | EP | disclosed |
| EP-0428019-A1 | Polyethersulfone-polyarylenesulfide block copolymers and process for making them | BAYER AG (DE) | 1991-05-22 | — | — | EP | disclosed |
| EP-0214470-B1 | PROCESS FOR THE PREPARATION OF POLYARYLENE SULFIDES | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0381867-A2 | Polyether ether ketone-polyarylene sulfide block copolymers | BAYER AG (DE) | 1990-08-16 | — | — | EP | disclosed |
| EP-0336240-A2 | Poly(arylene sulphides) with lowered temperature of crystallization and process for preparing them | BAYER AG (DE) | 1989-10-11 | — | — | EP | disclosed |
| EP-0215273-B1 | PROCESS FOR THE PREPARATION OF A HIGH MOLECULAR WEIGHT, POSSIBLY BRANCHED POLYARYLENE SULFIDE | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4760128-A | Reacting dihalogenaromatics, an alkali metal sulfide in in presence of a monomercapto compound | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| US-4760127-A | Reacting dihalogen aromatics and alkali metal sulfide in presence of a monohalogen compound and a monomercapto compound | BAYER AG (DE) | 1988-07-26 | — | — | US | disclosed |
| EP-0215273-A1 | Process for the preparation of a high molecular weight, possibly branched polyarylene sulfide | BAYER AG (DE) | 1987-03-25 | — | — | EP | disclosed |
| EP-0214470-A1 | Process for the preparation of polyarylene sulfides | BAYER AG (DE) | 1987-03-18 | — | — | EP | disclosed |
| US-4082793-A | AROMATIC PHOSPHINIC ACIDS CONTAINING SULFONE LINKAGE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012134-A1 | Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists | HTR2A, HTR2C, HTR2B | HTR6 14/4885ALDH1A1 594/4885SMN1; SMN2 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.