SCHEMBL636314

SCHEMBL636314

O=S(=O)(c1ccc(S)cc1)c1ccc(S)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HTR6 P50406 4/20 0.52
CYP3A4 P08684 2/20 0.52
GAA P10253 2/20 0.52
MAPK1 P28482 1/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
CYP2C9 P11712 1/20 0.52
TSHR P16473 1/20 0.52
PKM P14618 4/20 0.46
MAPT P10636 3/20 0.43
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
IDO1 P14902 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6006737 1.00 ALDH1A1 (0.52) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL947085 0.89 HTR6 (0.70) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL9187794 0.87 HSD11B1 (0.47) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL20108534 0.87 CA2 (0.50) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL9326670 0.87 ALDH1A1 (0.76) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL331401 0.87 GAA (0.55) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL25819444 0.87 GAA (0.76) ALDH1A1CYP3A4GAACYP2C9PKM
SCHEMBL27090263 0.85 HTT (0.55) ALDH1A1CYP3A4GAAMAPK1LMNA
SCHEMBL16435171 0.85 APEX1 (0.45) ALDH1A1HTR6CYP3A4GAAMAPK1
SCHEMBL27844440 0.83 HTR6 (0.54) ALDH1A1HTR6GAAPKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008903-A1 POLYTHIOL COMPOSITION AND USE THEREOF Efirm New Material Co., Ltd. (CN) 2026-01-08 US claimed
CN-120040703-A Polythiol composition, polymerizable composition for optical product, and optical product 益丰新材料股份有限公司 2025-05-27 CN claimed
CN-116768847-B Thiol composition and application thereof in optical material 益丰新材料股份有限公司 2025-04-29 CN claimed
CN-119751323-A Preparation method of polythiol compound 益丰新材料股份有限公司 2025-04-04 CN claimed
CN-118684609-A Polythiol compound for avoiding explosion polymerization and material leakage and application thereof 益丰新材料股份有限公司 2024-09-24 CN claimed
WO-2024188359-A1 POLYTHIOL COMPOSITION AND USE THEREOF 益丰新材料股份有限公司 2024-09-19 WO claimed
CN-117285688-B Polythiol composition and application thereof 益丰新材料股份有限公司 2024-08-30 CN claimed
CN-118063723-A Polythiol composition, preparation method and application thereof, and optical material 益丰新材料股份有限公司 2024-05-24 CN claimed
CN-117326997-A Polythiol compound, composition for optical material, and preparation method and application thereof 益丰新材料股份有限公司 2024-01-02 CN claimed
CN-117304082-A Polythiol compound for optical resin lens, optical resin lens and preparation method of optical resin lens 益丰新材料股份有限公司 2023-12-29 CN claimed
CN-117186057-A Polythiol composition and application thereof 益丰新材料股份有限公司 2023-12-08 CN claimed
CN-116768847-A Thiol composition and application thereof in optical material 益丰新材料股份有限公司 2023-09-19 CN claimed
CN-116640361-A Release agent composition and application thereof 益丰新材料股份有限公司 2023-08-25 CN claimed
WO-2023147792-A1 POLYTHIOL COMPOSITION AND USE THEREOF 益丰新材料股份有限公司 2023-08-10 WO claimed
CN-114790269-A Polythiol composition and application thereof 益丰新材料股份有限公司 2022-07-26 CN claimed
US-11377433-B2 Method for producing polyfunctional sulfur-containing epoxy compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-07-05 US claimed
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
WO-2006066569-A2 IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS HÄRING, Thomas (DE) 2006-06-29 WO claimed
EP-0219934-B1 PROCESS FOR THE PREPARATION OF ARYL-PIPERIDINE ESTERS BEECHAM GROUP PLC (GB) 1991-10-30 EP claimed
US-3949002-A POLYMER AND PHARMACEUTICAL INTERMEDIATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-04-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008903-A1 POLYTHIOL COMPOSITION AND USE THEREOF PARG, C5, TAF1 ALDH1A1 3748/4885HTR6 3968/4885CYP3A4 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.