Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814712 | 0.86 | ACE (0.64) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL9470471 | 0.84 | NR1D1 (0.47) | ACEABCB11 | |
| SCHEMBL14862925 | 0.80 | NPSR1 (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL30314166 | 0.80 | NPSR1 (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL1052393 | 0.80 | NPSR1 (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL3629346 | 0.80 | NPSR1 (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL29401156 | 0.80 | NPSR1 (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL7274646 | 0.79 | ACE (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL7274651 | 0.79 | ACE (0.62) | ACEABCB11POLBTDP1L3MBTL1 | |
| SCHEMBL27431282 | 0.79 | ACE (0.62) | ACEABCB11POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200416-A | CYCLIC AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1993-04-06 | — | — | US | disclosed |
| EP-0039804-A1 | Cyclic amides | USV PHARMACEUTICAL CORPORATION (US) | 1981-11-18 | — | — | EP | disclosed |