Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | TK2 | O00142 | 1/20 | 0.40 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470932 | 1.00 | LMNA (0.53) | LMNASMN1; SMN2ALOX12ADRA1AKMT2A | |
| SCHEMBL9470627 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2ALOX12ADRA1AKMT2A | |
| SCHEMBL9470617 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2ALOX12ADRA1AKMT2A | |
| SCHEMBL11144505 | 0.88 | LMNA (0.48) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL11144500 | 0.88 | LMNA (0.48) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL9443821 | 0.88 | RNASE1 (0.48) | LMNASMN1; SMN2TK1CYP1A2CYP3A4 | |
| SCHEMBL21563855 | 0.88 | RNASE1 (0.48) | LMNASMN1; SMN2TK1CYP1A2CYP3A4 | |
| SCHEMBL4728022 | 0.88 | TK1 (0.53) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL537189 | 0.88 | RNASE1 (0.48) | LMNASMN1; SMN2TK1CYP1A2CYP3A4 | |
| SCHEMBL2922542 | 0.87 | TK1 (0.42) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60061591-A | — | — | None | — | — | JP | disclosed |
| US-5250673-A | Antitumor agents | TAIHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0331032-B1 | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5032680-A | Antitumor | KURARAY CO., LTD. (JP) | 1991-07-16 | — | — | US | disclosed |
| US-4886877-A | Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0331032-A1 | 2'-Deoxy-5-fluorouridine derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |
| EP-0129984-B1 | NOVEL 2'-DEOXY-5-SUBSTITUTED URIDINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-03-02 | — | — | EP | disclosed |
| JP-S6061591-A | 2'-DEOXY-5-FLUOROURIDINE DERIVATIVE, ITS PREPARATION AND ANTITUMOR AGENT CONTAINING THE SAME | TAIHO YAKUHIN KOGYO KK | 1985-04-09 | — | — | JP | disclosed |
| EP-0129984-A1 | Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1985-01-02 | — | — | EP | disclosed |