Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9044170 | 0.87 | CYP26A1 (0.36) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9047678 | 0.87 | MAPK14 (0.34) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9471199 | 0.81 | TAS1R3 (0.41) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9045884 | 0.80 | MAPK14 (0.31) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9776186 | 0.79 | L3MBTL1 (0.32) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9471023 | 0.79 | KMT2A (0.43) | ALDH1A1L3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL9044092 | 0.77 | MAPK14 (0.32) | MAPK14ALDH1A1MAPK1 | |
| SCHEMBL9045359 | 0.77 | MAPK14 (0.36) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9471659 | 0.74 | TAS1R3 (0.40) | MAPK14TAS1R3TAS1R1ALDH1A1L3MBTL1 | |
| SCHEMBL9471269 | 0.74 | APP (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248775-A | Pyrrolo(2,3-d)pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1993-09-28 | — | — | US | disclosed |