Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491502 | 0.93 | FAAH (0.49) | GAAMAPTBCHEALDH1A1LMNA | |
| SCHEMBL9471202 | 0.92 | FAAH (0.51) | GAAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL6696112 | 0.82 | KMT2A (0.46) | GAAALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8840792 | 0.80 | ALDH1A1 (0.46) | GAAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL2546469 | 0.78 | STS (0.42) | GAAMAPTALDH1A1LMNAFAAH | |
| SCHEMBL26135537 | 0.77 | ALDH1A1 (0.47) | GAAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL20594029 | 0.77 | ALDH1A1 (0.47) | GAAMAPTALDH1A1LMNAKDM4E | |
| SCHEMBL9471337 | 0.77 | PTGIR (0.52) | GAAMAPTBCHEALDH1A1LMNA | |
| SCHEMBL2541972 | 0.76 | IDO1 (0.45) | GAAALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL2540533 | 0.76 | CYP19A1 (0.52) | ALDH1A1LMNAKDM4ESMN1; SMN2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223529-A | Nervous system and gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1993-06-29 | — | — | US | disclosed |