SCHEMBL8840792

SCHEMBL8840792

O=C(CNc1ccccc1)OO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
MAPT P10636 3/20 0.46
RAB9A P51151 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ERCC1 P07992 4/20 0.45
ERCC4 Q92889 4/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
HPGD P15428 1/20 0.45
AGTR1 P30556 1/20 0.45
PKM P14618 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
AKR1C3 P42330 1/20 0.43
ROCK2 O75116 1/20 0.43
GRK2 P25098 1/20 0.43
PTPN7 P35236 1/20 0.42
PTPN12 Q05209 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20594029 0.85 ALDH1A1 (0.47) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL26135537 0.85 ALDH1A1 (0.47) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL658053 0.83 LMNA (0.54) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL17527568 0.82 ALDH1A1 (0.45) ALDH1A1MAPTRAB9ALMNAMEN1
Benzene SCHEMBL28330086 0.82 LMNA (0.53) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL11416059 0.82 ALDH1A1 (0.45) ALDH1A1MAPTRAB9ALMNAMEN1
Hydrochloric Acid SCHEMBL76327 0.82 LMNA (0.53) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL2238017 0.82 ALDH1A1 (0.46) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL28554321 0.82 ALDH1A1 (0.45) ALDH1A1MAPTRAB9ALMNAMEN1
SCHEMBL150957 0.82 ALDH1A1 (0.45) ALDH1A1MAPTRAB9ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119198790-A Parhydroxyphenylglycine fermentation enzyme sample detection device 上海邦林生物科技有限公司 2024-12-27 CN claimed
CN-115784796-A Preparation method of chelated fertilizer for improving chelating capacity of trace elements of compound fertilizer 辽宁津大肥业有限公司 2023-03-14 CN disclosed
CN-109371095-B Method for synthesizing amoxicillin by enzyme method 广州市力鑫药业有限公司 2021-08-20 CN disclosed
CN-107674179-B Method for preparing epoxy resin by utilizing solid waste residues generated in production of p-hydroxyphenylglycine 天津市职业大学 2020-07-17 CN disclosed
CN-105949100-A Process for producing novel dithiocarbamate heavy metal chelating agents 浙江云涛生物技术股份有限公司 2016-09-21 CN disclosed
CN-103045474-A Recovery equipment and technology for hydroxy phenylglycine in amoxicillin synthetic mother solution XIAMEN TQX MEMBRANE TECHNOLOGY LTD 2013-04-17 CN disclosed
CN-103045474-A Recovery equipment and technology for hydroxy phenylglycine in amoxicillin synthetic mother solution XIAMEN TQX MEMBRANE TECHNOLOGY LTD 2013-04-17 CN disclosed
US-5595878-A Detection of biopolymers and biooligomers with boron hydride labels BORON BIOLOGICALS, INC. (US) 1997-01-21 US disclosed
EP-0480969-A4 AMINO ACID ANALOG CCK ANTAGONISTS 1993-01-07 EP disclosed
EP-0480969-A1 AMINO ACID ANALOG CCK ANTAGONISTS ABBOTT LABORATORIES (US) 1992-04-22 EP disclosed