SCHEMBL947293

SCHEMBL947293

O=C(Cl)c1ccc([N+](=O)[O-])cc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
KMT2A Q03164 6/20 0.51
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
ALOX15 P16050 2/20 0.49
CYP3A4 P08684 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
RORC P51449 1/20 0.46
MEN1 O00255 4/20 0.45
MAPT P10636 6/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPK1 P28482 1/20 0.43
CES2 O00748 1/20 0.43
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284069 0.86 ALDH1A1 (0.55) ALDH1A1KMT2ATSHRHIF1AALOX15
SCHEMBL20560158 0.84 ALDH1A1 (0.49) ALDH1A1KMT2ATSHRHIF1AALOX15
SCHEMBL77925 0.84 ALDH1A1 (0.64) ALDH1A1KMT2AHIF1AALOX15CYP3A4
SCHEMBL25837924 0.84 ALDH1A1 (0.64) ALDH1A1KMT2AHIF1AALOX15CYP3A4
SCHEMBL10694655 0.83 ALDH1A1 (0.57) ALDH1A1KMT2ATSHRALOX15CYP3A4
SCHEMBL1360146 0.82 MAPT (0.56) ALDH1A1KMT2ATSHRHIF1AALOX15
SCHEMBL31509357 0.82 MAPT (0.56) ALDH1A1KMT2ATSHRHIF1AALOX15
Hydrochloric Acid SCHEMBL17164230 0.82 ALDH1A1 (0.62) ALDH1A1KMT2AHIF1AALOX15CYP3A4
SCHEMBL114077 0.82 KMT2A (0.65) ALDH1A1KMT2ATSHRHIF1AALOX15
SCHEMBL20065126 0.81 KMT2A (0.51) ALDH1A1KMT2AHIF1AALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 CN claimed
CN-116178203-A Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2023-05-30 CN claimed
EP-4748837-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-05-27 EP disclosed
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE BAERENKRAFT THERAPEUTICS LLC (US) 2026-04-23 US disclosed
CN-119954850-A Fluorinated diamine monomer, slurry and polyimide film 奥克控股集团股份公司 2025-05-09 CN disclosed
CN-119954849-A Diamine monomer, slurry and polyimide film 奥克控股集团股份公司 2025-05-09 CN disclosed
CN-115066417-B Factor XIa inhibitors 上海京新生物医药有限公司 2025-05-02 CN disclosed
CN-119874680-A 2-Aminopyrimidine compound containing 2-chloroacrylamide, preparation method and application thereof 浙大城市学院 2025-04-25 CN disclosed
CN-116354845-B Compound with function of resisting Fusobacterium nucleatum and application thereof 中国人民解放军海军军医大学 2025-03-07 CN disclosed
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 CN disclosed
WO-2025021003-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 浙江海正药业股份有限公司 2025-01-30 WO disclosed
EP-0843671-A1 HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 1998-05-27 EP disclosed
EP-0601813-B1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORP (JP) 1997-08-13 EP disclosed
WO-1997003069-A1 HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 1997-01-30 WO disclosed
WO-1996015115-A1 HERBICIDAL PYRAZOLE COMPOUNDS ZENECA LIMITED (GB) 1996-05-23 WO disclosed
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed
EP-0696270-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1996-02-14 EP disclosed
US-5382688-A Diamino compounds and their production method CHISSO CORPORATION (JP) 1995-01-17 US disclosed
WO-1994025429-A1 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1994-11-10 WO disclosed
EP-0601813-A1 Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1994-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109690-A1 HDAC6 INHIBITORS AND METHOD OF THEIR USE HDAC6, HDAC3, HDAC1 ALDH1A1 1331/4885KMT2A 243/4885TSHR 1872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.