SCHEMBL10694655

SCHEMBL10694655

O=C(Cl)c1ccc([N+](=O)[O-])cc1C(=O)Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
KMT2A Q03164 2/20 0.56
TSHR P16473 4/20 0.55
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MAPT P10636 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
HSD17B10 Q99714 1/20 0.48
TP53 P04637 3/20 0.46
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
PKM P14618 1/20 0.46
NFKB1 P19838 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547738 0.85 ALDH1A1 (0.51) ALDH1A1KMT2ATSHRTDP1MAPT
SCHEMBL752917 0.85 KMT2A (0.72) ALDH1A1KMT2ATSHRTDP1MAPT
SCHEMBL2243892 0.85 GPR35 (0.56) ALDH1A1KMT2ATSHRCYP3A4ALOX15
SCHEMBL4954263 0.85 L3MBTL1 (0.63) ALDH1A1KMT2ATSHRCYP3A4TDP1
SCHEMBL1644789 0.85 GPR35 (0.56) ALDH1A1KMT2ATSHRCYP3A4ALOX15
SCHEMBL398463 0.85 HSD17B10 (0.60) ALDH1A1KMT2ATSHRCYP3A4ALOX15
SCHEMBL3126462 0.85 CES2 (0.59) ALDH1A1KMT2ATSHRCYP3A4ALOX15
SCHEMBL8537297 0.84 MAPT (0.58) ALDH1A1KMT2ATSHRCYP3A4MAPT
SCHEMBL947293 0.83 ALDH1A1 (0.52) ALDH1A1KMT2ATSHRCYP3A4ALOX15
SCHEMBL510143 0.83 ALDH1A1 (0.58) ALDH1A1KMT2ATSHRCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102574-B 4-Nitrophthaloyl nitrogen oxygen heterocyclic compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2025-02-11 CN disclosed
CN-116041372-B Sulfur-nitrogen heterocyclic alkane intermediate compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2025-02-11 CN disclosed
CN-115925713-B Diazamacrocyclic compound intermediate, and preparation method and application thereof 苏州百灵威超精细材料有限公司 2024-12-24 CN disclosed
CN-115557967-B 4-Nitrophthaloyl aza crown ether compound, preparation method and application 苏州百灵威超精细材料有限公司 2024-07-02 CN disclosed
CN-116102574-A 4-nitrophthaloyl nitrogen oxygen heterocyclic compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-05-12 CN disclosed
CN-116041372-A Sulfur-nitrogen heterocyclic alkane intermediate compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-05-02 CN disclosed
CN-115925713-A Diazacyclocycle compound intermediate and preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-04-07 CN disclosed
CN-115557967-A 4-nitrophthaloyl aza crown ether compound, preparation method and application thereof 苏州百灵威超精细材料有限公司 2023-01-03 CN disclosed
CN-106750322-B A kind of polyoxometallate-caged silsesquioxane hybrid and preparation method thereof 南开大学 2019-06-04 CN disclosed
US-8658433-B2 Dye compounds as photoactive agents MALLINCKRODT LLC (US) 2014-02-25 US disclosed
CN-100443464-C AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2008-12-17 CN disclosed
CN-1865225-A AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2006-11-22 CN disclosed
US-4739062-A REACTING AN AROMATIC COMPOUND WITH DICARBOXYLIC ACID COMPOUND USING METAL HALIDE CATALYST CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1988-04-19 US disclosed