SCHEMBL284069

SCHEMBL284069

O=C(Cl)c1cc([N+](=O)[O-])ccc1F

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.55
HIF1A Q16665 1/20 0.55
TSHR P16473 1/20 0.50
RORC P51449 1/20 0.49
MAPT P10636 7/20 0.48
KMT2A Q03164 5/20 0.48
MEN1 O00255 3/20 0.48
HTT P42858 2/20 0.48
GAA P10253 1/20 0.47
ALOX15 P16050 2/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP3A4 P08684 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL947293 0.86 ALDH1A1 (0.52) ALDH1A1HIF1ATSHRRORCMAPT
SCHEMBL20560735 0.84 ALDH1A1 (0.53) ALDH1A1HIF1ATSHRRORCMAPT
SCHEMBL1654660 0.84 ALDH1A1 (0.59) ALDH1A1HIF1AMAPTKMT2AMEN1
SCHEMBL195145 0.84 ALDH1A1 (0.59) ALDH1A1HIF1AMAPTKMT2AMEN1
SCHEMBL10694655 0.83 ALDH1A1 (0.57) ALDH1A1TSHRRORCMAPTKMT2A
SCHEMBL13844206 0.82 KMT2A (0.60) ALDH1A1HIF1ATSHRKMT2AMEN1
Silver SCHEMBL887047 0.82 ALDH1A1 (0.55) ALDH1A1HIF1ARORCMAPTKMT2A
SCHEMBL887048 0.82 ALDH1A1 (0.57) ALDH1A1HIF1AMAPTKMT2AMEN1
SCHEMBL4485751 0.82 KMT2A (0.60) ALDH1A1HIF1ATSHRKMT2AMEN1
SCHEMBL2832 0.82 ALDH1A1 (0.55) ALDH1A1HIF1ARORCMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 CN claimed
CN-116178203-A Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2023-05-30 CN claimed
CN-110305100-B Near-infrared poly-hydrogen sulfide fluorescent probe and preparation method and application thereof 徐州医科大学 2022-04-29 CN claimed
CN-110305100-A A kind of poly- hydrogen sulfide fluorescence probe of near-infrared and its preparation method and application 徐州医科大学 2019-10-08 CN claimed
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES UNIV YALE (US) 2026-04-30 US disclosed
US-12509436-B2 Benzamide derivatives as cGAS-sting pathway agonists BARUCH S. BLUMBERG INSTITUTE (US) 2025-12-30 US disclosed
EP-4644362-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH Intervet International B.V. (NL) 2025-11-05 EP disclosed
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 CN disclosed
US-11986531-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides ARVINAS OPERATIONS, INC. (US) 2024-05-21 US disclosed
US-20240116854-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH INTERVET INC. (US) 2024-04-11 US disclosed
WO-2024028169-A1 NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-02-08 WO disclosed
CN-117241669-A Cyclopropylamide compounds against parasites in fish 英特威国际有限公司荷兰疫苗厂 2023-12-15 CN disclosed
CN-1273585-A Substituted 3- (1, 2-benzisothiazole or isoxazol-5-yl) -substituted pyrimidines as herbicides AMERICAN CYANAMID CO (US) 2000-11-15 CN disclosed
CN-1214339-A Pyrazole derivatives, their preparation and their use in pharmaceuticals HOECHST MARION ROUSSEL DE GMBH (DE) 1999-04-21 CN disclosed
EP-0908456-A1 Pyrazole derivatives, their preparation and their use in drugs Hoechst Marion Roussel Deutschland GmbH (DE) 1999-04-14 EP disclosed
US-RE32975-E FUNGICIDES, BACTERICIDES, FEED ADDITIVES BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
US-4801717-A PLANT GROWTH REGULATORS ROUSSEL UCLAF (FR) 1989-01-31 US disclosed
EP-0004279-B1 PROCESS FOR THE PREPARATION OF 4-PYRIDONE-3-CARBOXYLIC ACIDS, 1-CYCLOPROPYL-4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES AND MEDICINES CONTAINING THEM BAYER AG (DE) 1982-12-29 EP disclosed
US-4284629-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
EP-0004279-A1 Process for the preparation of 4-pyridone-3-carboxylic acids, 1-cyclopropyl-4-pyridone-3-carboxylic acid derivatives and medicines containing them BAYER AG (DE) 1979-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116854-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH PIGO, PPIA, PPT1 ALDH1A1 623/4885HIF1A 1701/4885TSHR 2266/4885
US-12509436-B2 Benzamide derivatives as cGAS-sting pathway agonists STING1, CGAS, IFNAR1 ALDH1A1 4236/4885HIF1A 1139/4885TSHR 913/4885
US-11986531-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides CRBN, ARAF, VHL ALDH1A1 2833/4885HIF1A 2237/4885TSHR 2304/4885
US-20260115296-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, VHL, ADRM1 ALDH1A1 2777/4885HIF1A 2102/4885TSHR 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.