Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864527 | 0.77 | KDM1A (0.53) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL11050112 | 0.71 | ALDH1A1 (0.46) | EGFRERBB2KDM4EGLAMAPT | |
| SCHEMBL11166383 | 0.70 | KDM1A (0.53) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL31121011 | 0.68 | EGFR (0.46) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL9356235 | 0.68 | EGFR (1.00) | EGFRERBB2ERBB3KDRPTK2 | |
| SCHEMBL24041241 | 0.67 | KDM1A (0.46) | EGFRERBB2KDM4EMAPTALDH1A1 | |
| SCHEMBL11124065 | 0.66 | KDM1A (0.46) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL22331106 | 0.66 | L3MBTL1 (0.42) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL22331104 | 0.63 | MC4R (0.45) | ALDH1A1HPGDNPSR1 | |
| SCHEMBL11153238 | 0.63 | L3MBTL1 (0.40) | KDM4EGLAMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221595-A | Printing plates, photoresist; high photosensitivity, acid resistance | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| US-4250053-A | WITH FLUORESCENT COMPOUND | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-02-10 | — | — | US | disclosed |