Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474084 | 1.00 | MEN1 (0.42) | MEN1KMT2ASCN3AITGA4ITGB7 | |
| SCHEMBL9856770 | 0.95 | ITGA4 (0.44) | ITGA4ITGB7ITGB1 | |
| SCHEMBL9473565 | 0.94 | SCN3A (0.41) | MEN1KMT2ASCN3AITGA4ITGB7 | |
| SCHEMBL9857334 | 0.93 | SCN3A (0.41) | MEN1KMT2ASCN3AITGA4ITGB1 | |
| SCHEMBL9857009 | 0.93 | SCN3A (0.41) | MEN1KMT2ASCN3AITGA4ITGB1 | |
| SCHEMBL9473272 | 0.91 | MAPT (0.45) | MEN1KMT2ASCN3AITGA4ITGB7 | |
| SCHEMBL9473551 | 0.88 | ITGB2 (0.49) | — | |
| SCHEMBL9473540 | 0.88 | TP53 (0.35) | MEN1KMT2AITGA4ITGB7GPR132 | |
| SCHEMBL9473700 | 0.87 | CDK2 (0.42) | — | |
| SCHEMBL9474710 | 0.87 | TP53 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234917-A | Hypotensive agent, treatment of renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION | 1993-08-10 | — | — | US | disclosed |
| US-5231184-A | Viricide intermediate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-27 | — | — | US | disclosed |
| US-5106973-A | Viricide intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-21 | — | — | US | disclosed |
| EP-0437103-A2 | Substituted 5-(alkyl)carboxamide imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |
| US-4992433-A | Viricides | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-02-12 | — | — | US | disclosed |