Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473345 | 0.78 | PDE4A (0.38) | ALDH1A1ATMTDP1L3MBTL1MEN1 | |
| SCHEMBL9473365 | 0.78 | TDP1 (0.40) | ALDH1A1ATMTDP1L3MBTL1HSD17B10 | |
| SCHEMBL9473463 | 0.77 | PDE4A (0.40) | ALDH1A1ATMTDP1L3MBTL1KDM4E | |
| SCHEMBL9473473 | 0.77 | POLB (0.42) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL9473163 | 0.77 | SQOR (0.43) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL9473315 | 0.76 | RGS4 (0.39) | ALDH1A1ATMTDP1L3MBTL1KDM4E | |
| SCHEMBL9473415 | 0.72 | RGS4 (0.36) | ALDH1A1CNR2ATMTDP1L3MBTL1 | |
| SCHEMBL8332355 | 0.71 | GSK3A (0.42) | HSD17B10TSHRHPGDKMT2ALMNA | |
| SCHEMBL21407956 | 0.68 | RGS4 (0.46) | ALDH1A1ATMTDP1L3MBTL1KDM4E | |
| SCHEMBL11633842 | 0.67 | NTRK1 (0.48) | ALDH1A1ATMTDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000897-A1 | METHOD FOR THE CONTROL OF HYPERLIPIDEMIA | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1990-02-08 | — | — | WO | claimed |
| US-4866058-A | TRIAZOLIDINE-BIONES, TRIAZABICYCLOHEXANEDIONES, AND TRIAZINE-DIONES | NORTH CAROLINA AT CHAPEL HILL, THE UNIVERSITY OF | 1989-09-12 | — | — | US | claimed |
| US-5192761-A | 1,2,4-triazolidine-3,5-diones and 1,3,5-triazine-2,4(1-H,3H)-diones, pharmaceutical compositions | NORTH CAROLINA CENTRAL UNIV. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5034528-A | 1,3,5-triazabicyclo 3.1.0!hexane-3,5-diones | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 1991-07-23 | — | — | US | disclosed |
| WO-1990000897-A1 | METHOD FOR THE CONTROL OF HYPERLIPIDEMIA | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1990-02-08 | — | — | WO | disclosed |
| US-4866058-A | TRIAZOLIDINE-BIONES, TRIAZABICYCLOHEXANEDIONES, AND TRIAZINE-DIONES | NORTH CAROLINA AT CHAPEL HILL, THE UNIVERSITY OF | 1989-09-12 | — | — | US | disclosed |