Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856406 | 0.78 | — | — | |
| SCHEMBL9856774 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL6968208 | 0.73 | TLR8 (0.45) | ALDH1A1AGTR1LMNAHPGD | |
| SCHEMBL9857429 | 0.72 | SCN3A (0.44) | KMT2A | |
| SCHEMBL7216579 | 0.72 | TLR8 (0.41) | ALDH1A1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL7270215 | 0.71 | AGTR1 (0.47) | ALDH1A1AGTR1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL7631242 | 0.71 | HTR2A (0.40) | ALDH1A1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL9473536 | 0.70 | BRS3 (0.33) | — | |
| SCHEMBL9856773 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HTR2AHTR2CSLC6A4LMNA | |
| SCHEMBL9422754 | 0.67 | NOTUM (0.44) | ALDH1A1AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234917-A | Hypotensive agent, treatment of renal failure or glaucoma | SMITHKLINE BEECHAM CORPORATION | 1993-08-10 | — | — | US | disclosed |
| EP-0437103-A2 | Substituted 5-(alkyl)carboxamide imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-17 | — | — | EP | disclosed |