Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473579 | 0.83 | MAPK14 (0.39) | MAPTALDH1A1HPGDMAPK14CHRNA7 | |
| SCHEMBL9587856 | 0.74 | SMN1; SMN2 (0.52) | MAPTALDH1A1HPGDMAPK14EPHX2 | |
| SCHEMBL9473989 | 0.72 | SMN1; SMN2 (0.68) | HPGDMAPK14EPHX2NR1H4CHRM4 | |
| SCHEMBL9587376 | 0.72 | L3MBTL1 (0.53) | MAPTALDH1A1HPGDMAPK14CHRNA7 | |
| SCHEMBL9587518 | 0.72 | L3MBTL1 (0.53) | MAPTALDH1A1HPGDMAPK14CHRNA7 | |
| SCHEMBL920312 | 0.68 | HPGD (0.50) | MAPTALDH1A1HPGDMAPK14EPHX2 | |
| SCHEMBL9474213 | 0.67 | CHRM4 (0.53) | MAPTALDH1A1HPGDMAPK14EPHX2 | |
| SCHEMBL29260504 | 0.64 | MAPT (0.59) | MAPTALDH1A1HPGDEPHX2NR1H4 | |
| SCHEMBL6017524 | 0.64 | KMT2A (0.59) | MAPTALDH1A1HPGDEPHX2NR1H4 | |
| SCHEMBL921176 | 0.63 | HPGD (0.54) | MAPTALDH1A1HPGDSMN1; SMN2LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264448-A | Thioamides, oxazole ring, insecticides, miticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0394043-A1 | An amide compound and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |