Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473989 | 0.89 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAKMT2AGALR3NR2F2 | |
| SCHEMBL9587518 | 0.80 | L3MBTL1 (0.53) | SMN1; SMN2CHRM4EPHX2NR1H4TP53 | |
| SCHEMBL9587376 | 0.80 | L3MBTL1 (0.53) | SMN1; SMN2CHRM4EPHX2NR1H4TP53 | |
| SCHEMBL9587863 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAKMT2AGALR3NR2F2 | |
| SCHEMBL9473513 | 0.75 | LMNA (0.60) | SMN1; SMN2LMNAKMT2AGALR3NR2F2 | |
| SCHEMBL9474213 | 0.75 | CHRM4 (0.53) | SMN1; SMN2LMNACHRM4EPHX2NR1H4 | |
| SCHEMBL9473560 | 0.74 | MAPT (0.43) | SMN1; SMN2KMT2ACHRM4EPHX2NR1H4 | |
| Tolfenpyrad SCHEMBL26416 | 0.72 | RAB9A (0.57) | SMN1; SMN2LMNAKMT2AGALR3NR2F2 | |
| SCHEMBL920312 | 0.72 | HPGD (0.50) | SMN1; SMN2KMT2ACHRM4EPHX2NR1H4 | |
| SCHEMBL6273314 | 0.70 | TP53 (0.52) | SMN1; SMN2LMNAKMT2ARAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206259-A | Insecticides, acaricides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-27 | — | — | US | claimed |
| US-5206259-A | Insecticides, acaricides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |