Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1794070 | 0.96 | TSHR (0.41) | TSHR | |
| SCHEMBL20742048 | 0.84 | TSHR (0.43) | TSHRSRC | |
| SCHEMBL21045764 | 0.81 | CA2 (0.35) | TSHRSRCTP53 | |
| SCHEMBL28108170 | 0.79 | CA2 (0.33) | TSHR | |
| SCHEMBL3634910 | 0.76 | TSHR (0.39) | TSHRTP53 | |
| SCHEMBL9437852 | 0.76 | TSHR (0.39) | TSHR | |
| SCHEMBL11276029 | 0.69 | TSHR (0.33) | TSHRTP53 | |
| SCHEMBL23499619 | 0.68 | PDE4A (0.35) | TSHR | |
| SCHEMBL4896921 | 0.68 | PDE4A (0.48) | — | |
| SCHEMBL915072 | 0.68 | TSHR (0.53) | TSHRSRCTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200423-A | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |