Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.73 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.73 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CDK2 | P24941 | 1/20 | 0.70 |
| ▸ | CDK1 | P06493 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL7891002 | 0.86 | PI4KA (0.56) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL29557469 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL37358 | 0.84 | LMNA (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL104931 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL27965572 | 0.84 | LMNA (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL29349525 | 0.84 | LMNA (1.00) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL27546509 | 0.83 | TSHR (0.70) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL30241517 | 0.83 | LMNA (0.97) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL8378682 | 0.83 | LMNA (0.97) | PDE4APDE4BPDE4CPDE4DLMNA | |
| 6-Benzylaminopurine SCHEMBL218733 | 0.83 | LMNA (0.97) | PDE4APDE4BPDE4CPDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5211738-A | ADENINE DERIVATIVES AND THEIR USE AS A PLANT GROWTH REGULATOR | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0508777-A2 | Novel adenine derivatives and their use as plant growth regulators | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-10-14 | — | — | EP | disclosed |