SCHEMBL6936635

SCHEMBL6936635

Cc1ccc(C)c(/C=C/c2ccc(-c3ccc(/C=C/c4cc(C)ccc4C)cc3)cc2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.62
PTGS2 P35354 3/20 0.62
ALOX5 P09917 2/20 0.62
NFE2L2 Q16236 6/20 0.44
FGF23 Q9GZV9 1/20 0.40
RELA Q04206 2/20 0.39
KDM4E B2RXH2 3/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11414757 1.00 PTGS1 (0.62) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL30175764 1.00 PTGS1 (0.62) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL13808646 0.90 PTGS1 (0.53) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL16105742 0.84 ALOX5 (0.62) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL9474707 0.84 ALOX5 (0.62) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL9473335 0.84 ALOX5 (0.62) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL9474306 0.82 RELA (0.67) PTGS1PTGS2ALOX5NFE2L2RELA
SCHEMBL8885875 0.80 PTGS1 (0.54) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL8885870 0.80 PTGS1 (0.54) PTGS1PTGS2ALOX5NFE2L2FGF23
SCHEMBL11491919 0.79 RARA (0.40) PTGS1PTGS2ALOX5NFE2L2FGF23

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8766197-B2 Radiation detection element NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (JP) 2014-07-01 US disclosed
US-20120235046-A1 RADIATION DETECTION ELEMENT NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (JP) 2012-09-20 US disclosed
CN-1154852-C Self-scintillating sheet material for radioactive species analysis 3M 2004-06-23 CN disclosed
EP-1032850-B1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING & MFG (US) 2003-12-17 EP disclosed
EP-1183554-A1 IN-SITU RADIOACTIVITY DETECTION 3M Innovative Properties Company (US) 2002-03-06 EP disclosed
CN-1279767-A Self-scintillating sheet material for radioactive species analysis MINNESOTA MINING & MFG (US) 2001-01-10 CN disclosed
WO-2000077545-A1 IN-SITU RADIOACTIVITY DETECTION 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed
US-6139749-A CONTACTING ENVIRONMENTAL FLUID WITH COMPOSITE SHEET MATERIAL COMPRISING SEPARATORS AND SCINTILLATORS ENTRAPPED IN POROUS MATRIX OR MEMBRANE 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-31 US disclosed
EP-1032850-A1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-09-06 EP disclosed
WO-1999027387-A1 SELF-SCINTILLATING SHEET MATERIAL FOR RADIOACTIVE SPECIES ANALYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-03 WO disclosed
US-4217239-A Composition for scintillation counting CIBA-GEIGY CORPORATION (US) 1980-08-12 US disclosed