Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473353 | 0.88 | NOTUM (0.66) | POLBLMNATSHRALDH1A1NPC1 | |
| SCHEMBL9563666 | 0.84 | LMNA (0.57) | POLBLMNAMAPK1NPC1MAPT | |
| SCHEMBL5140151 | 0.81 | POLB (0.59) | POLBLMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL9958891 | 0.79 | POLB (0.60) | POLBLMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL9474574 | 0.78 | POLB (0.59) | POLBLMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL22406054 | 0.78 | POLB (0.59) | POLBLMNAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6032429 | 0.78 | HCAR2 (0.81) | HCAR2POLBTSHRMAPK10ALDH1A1 | |
| SCHEMBL8943790 | 0.77 | HCAR2 (0.79) | HCAR2POLBTSHRMAPK10ALDH1A1 | |
| SCHEMBL25195550 | 0.76 | POLB (0.54) | POLBLMNAALDH1A1MAPTKDM4E | |
| SCHEMBL9474708 | 0.76 | POLB (0.57) | POLBLMNAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217961-A | High carcinostatic activity; inhibiting KB-cell growth | MECT CORPORATION (JP) | 1993-06-08 | — | — | US | disclosed |