Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140151 | 0.81 | POLB (0.59) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9958891 | 0.79 | POLB (0.60) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14479863 | 0.78 | ALDH1A1 (0.78) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22406054 | 0.78 | POLB (0.59) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8485405 | 0.78 | LMNA (1.00) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9474574 | 0.78 | POLB (0.59) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL9474708 | 0.76 | POLB (0.57) | LMNAMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL9475267 | 0.75 | HCAR2 (0.56) | LMNANPC1POLBALDH1A1MAPK1 | |
| SCHEMBL9473982 | 0.75 | KMT2A (0.75) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4565884 | 0.74 | HDAC3 (0.57) | LMNAMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217961-A | High carcinostatic activity; inhibiting KB-cell growth | MECT CORPORATION (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0376166-A1 | Condensed quinoline system compound and process of preparation thereof | MECT CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |