Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TOP1 | P11387 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380299 | 0.90 | KCNH2 (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9475433 | 0.88 | KCNH2 (0.59) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL10643509 | 0.87 | ALDH1A1 (0.71) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9475565 | 0.84 | KCNH2 (0.48) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9475379 | 0.84 | POLB (0.45) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9473967 | 0.84 | KDM4E (0.62) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9477423 | 0.83 | ALDH1A1 (0.56) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9475669 | 0.82 | KDM4E (0.60) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9474713 | 0.82 | ALDH1A1 (0.55) | KCNH2ALDH1A1POLBOPRM1CHRM2 | |
| SCHEMBL9475648 | 0.82 | KCNH2 (0.74) | KCNH2ALDH1A1POLBOPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | claimed |
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |