Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 7/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.74 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | CLK2 | P49760 | 1/20 | 0.74 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12917214 | 0.90 | MEN1 (0.62) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL967940 | 0.89 | MEN1 (0.61) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29593740 | 0.89 | ALDH1A1 (0.81) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6783172 | 0.89 | ALDH1A1 (0.81) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10697767 | 0.89 | KDM4E (0.61) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9474947 | 0.88 | TOP2A (0.61) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9260082 | 0.88 | KCNH2 (0.69) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9475858 | 0.88 | KDM4E (0.57) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3957125 | 0.87 | ALDH1A1 (0.79) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9792010 | 0.87 | KCNH2 (0.79) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |