Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319952 | 0.80 | HSD17B10 (0.42) | — | |
| SCHEMBL27992652 | 0.70 | NPEPPS (0.34) | — | |
| SCHEMBL8679068 | 0.69 | NCF1 (0.48) | — | |
| SCHEMBL29773903 | 0.69 | HRH4 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8986585 | 0.69 | NCF1 (0.54) | — | |
| SCHEMBL2049800 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL31342013 | 0.67 | CYP11B1 (0.72) | CYP11B1CYP11B2TUBB4ATUBBTUBA3C | |
| Water SCHEMBL28778724 | 0.66 | MAPT (0.32) | — | |
| Hydrochloric Acid SCHEMBL28920941 | 0.66 | NPC1 (0.35) | — | |
| SCHEMBL4140323 | 0.66 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234873-A | — | — | None | — | — | JP | disclosed |
| US-5204472-A | For preparing inotropic agents; substituted dihydropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| JP-H04234873-A | NEW 4-QUINOLYL-DIHYDROPYRIDNE, ITS PRODUCTION AND USE IN MEDICINE | BAYER AG | 1992-08-24 | — | — | JP | disclosed |
| US-5100900-A | Inotropic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |