Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475516 | 0.80 | CYP11B1 (0.44) | — | |
| SCHEMBL21250754 | 0.78 | HSD17B10 (0.53) | HSD17B10TSHRHTR3EHTR3BCYP1A2 | |
| SCHEMBL27992652 | 0.75 | NPEPPS (0.34) | HSD17B10CYP1A2HTR2AHTR3AALDH1A1 | |
| SCHEMBL4216264 | 0.75 | HSD17B10 (0.48) | HSD17B10TSHRHTR3EHTR3BCYP1A2 | |
| SCHEMBL29958355 | 0.74 | — | — | |
| SCHEMBL7789812 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL9276325 | 0.74 | KEAP1 (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9276285 | 0.74 | MGLL (0.37) | — | |
| SCHEMBL1238592 | 0.74 | MGLL (0.37) | GSK3AGSK3BHCAR1 | |
| SCHEMBL28406341 | 0.74 | GAA (0.36) | HSD17B10CYP1A2CYP2D6NFKB1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197829-B1 | ARYLAMINE SYNTHESIS METHOD | CENTRE NAT RECH SCIENT (FR) | 2016-05-04 | — | — | EP | claimed |
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | SOLVAY (CHINA) CO., LTD (CN) | 2013-10-17 | — | — | US | claimed |
| US-8399680-B2 | Arylamine synthesis method | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2013-03-19 | — | — | US | claimed |
| US-20100298571-A1 | ARYLAMINE SYNTHESIS METHOD | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2010-11-25 | — | — | US | claimed |
| EP-0085185-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY LINEAR HIGH MOLECULAR WEIGHT THERMOPLASTIC POLYMERS FROM ARYL POLYHALIDE MONOMERS | AMOCO CORPORATION (US) | 1987-05-20 | — | — | EP | claimed |
| US-4400499-A | OXIDATIVE COUPLING | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | claimed |
| EP-0085185-A1 | Integrated process for the preparation of substantially linear high molecular weight thermoplastic polymers from aryl polyhalide monomers | AMOCO CORPORATION (US) | 1983-08-10 | — | — | EP | claimed |
| WO-2024081345-A1 | BENZOPYRIMIDIN-4(3H)-ONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2024-04-18 | — | — | WO | disclosed |
| WO-2024064024-A1 | ((4-OXO-3,4-DIHYDROQUINAZOLIN-8-YL)METHYL)AMINE DERIVATIVES AS P13K INHIBITORS FOR THE TREATMENT OF CANCER | ONKURE, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| WO-2023239710-A1 | BENZOPYRIMIDIN-4(3H)-ONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| EP-2043970-B1 | IRON-COPPER CO-CATALYZED PROCESS FOR CARBON-CARBON OR CARBON-HETEROATOM BONDING | CENTRE NAT RECH SCIENT (FR) | 2018-04-18 | — | — | EP | disclosed |
| US-9861971-B2 | Catalytic system for cross-coupling reactions | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2018-01-09 | — | — | US | disclosed |
| US-20160130205-A1 | CATALYTIC SYSTEM FOR CROSS-COUPLING REACTIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2016-05-12 | — | — | US | disclosed |
| EP-0025460-B1 | COUPLING OF ARYL AND HETEROARYL POLYHALIDES | AMOCO CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4579851-A | HYPOTENSIVE, ANTIARRHYTHMIA AGENTS | MERCK & CO., INC. (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0163238-A2 | Substituted and bridged pyridines useful as pharmaceutical agents | MERCK & CO. INC. (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4486576-A | NICKEL-CATALYZED COUPLING | UNION CARBIDE CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0095042-A1 | Aromatic coating materials from aryl polyhalides | UNION CARBIDE CORPORATION (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4400499-A | OXIDATIVE COUPLING | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0085185-A1 | Integrated process for the preparation of substantially linear high molecular weight thermoplastic polymers from aryl polyhalide monomers | AMOCO CORPORATION (US) | 1983-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | PHOSPHO1, ATIC, ACP1 | HSD17B10 3418/4885TSHR 2296/4885HTR3E 4598/4885 |
| US-20160130205-A1 | CATALYTIC SYSTEM FOR CROSS-COUPLING REACTIONS | HCCS, FECH, CTRC | HSD17B10 578/4885TSHR 2358/4885HTR3E 1948/4885 |
| US-20100298571-A1 | ARYLAMINE SYNTHESIS METHOD | NAT1, ASNS, AOC2 | HSD17B10 967/4885TSHR 1305/4885HTR3E 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.