Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 11/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 11/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475581 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KCNE1KCNQ1ESPL1KCNH2 | |
| SCHEMBL9475568 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KCNE1KCNQ1ESPL1KCNH2 | |
| Hydrochloric Acid SCHEMBL9478130 | 0.99 | ALDH1A1 (0.42) | ALDH1A1KCNE1KCNQ1ESPL1KCNH2 | |
| Hydrochloric Acid SCHEMBL9478145 | 0.99 | ALDH1A1 (0.42) | ALDH1A1KCNE1KCNQ1ESPL1KCNH2 | |
| Hydrochloric Acid SCHEMBL9478119 | 0.99 | ALDH1A1 (0.42) | ALDH1A1KCNE1KCNQ1ESPL1KCNH2 | |
| SCHEMBL9474403 | 0.88 | KCNE1 (0.38) | KCNE1KCNQ1KCNH2ABCC9KCNA5 | |
| SCHEMBL9474410 | 0.88 | KCNE1 (0.38) | KCNE1KCNQ1KCNH2ABCC9KCNA5 | |
| SCHEMBL9474414 | 0.88 | KCNE1 (0.38) | KCNE1KCNQ1KCNH2ABCC9KCNA5 | |
| SCHEMBL9200746 | 0.84 | KCNE1 (0.45) | KCNE1KCNQ1KCNH2ABCC9KCNA5 | |
| SCHEMBL9200749 | 0.84 | KCNE1 (0.45) | KCNE1KCNQ1KCNH2ABCC9KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254578-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1993-10-19 | — | — | US | disclosed |