Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9476598 | 0.91 | S100A4 (0.34) | KDM4EABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476478 | 0.86 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475563 | 0.81 | CHRM1 (0.31) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL9475319 | 0.81 | ABCC9 (0.31) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475265 | 0.79 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475710 | 0.79 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9478300 | 0.79 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476674 | 0.78 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9476029 | 0.78 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475069 | 0.77 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |