Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673847 | 0.82 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP2C9CYP2A6CYP2C19 | |
| SCHEMBL9476467 | 0.77 | LMNA (0.30) | — | |
| SCHEMBL3825216 | 0.72 | CYP2A6 (0.36) | ALDH1A1CYP2C9CYP2A6MEN1KMT2A | |
| SCHEMBL1922646 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL10699441 | 0.72 | APLNR (0.33) | — | |
| SCHEMBL4130371 | 0.72 | APLNR (0.40) | — | |
| SCHEMBL4133571 | 0.71 | PTGDR2 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7802400 | 0.71 | TSHR (0.35) | PTGFR | |
| SCHEMBL7792144 | 0.71 | SMN1; SMN2 (0.35) | PTGFR | |
| SCHEMBL4610096 | 0.70 | IDO1 (0.35) | ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196529-A | Grampositive antibacterial agents | MERCK & CO., INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5177202-A | 2-phenanthrenyl-carbapenems | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0464901-A2 | 2-phenanthrenyl carbapenems | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| EP-0463852-A2 | 2-Phenanthrenyl-carbapenem antibacterial agents | MERCK & CO. INC. (US) | 1992-01-02 | — | — | EP | disclosed |
| US-5004740-A | Carbapenicillin antibiotics | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-5004739-A | Dehydropeptidase inhibitor | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |