Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936621 | 0.79 | ALDH1A1 (0.43) | GAARAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL16238292 | 0.79 | PLCG1 (0.43) | PLCG1CYP11B1PKMRAB9ANPC1 | |
| SCHEMBL8710247 | 0.78 | S1PR4 (0.44) | ALOX5APFEN1GAARAB9ANPC1 | |
| SCHEMBL31437246 | 0.78 | S1PR4 (0.44) | ALOX5APFEN1GAARAB9ANPC1 | |
| SCHEMBL29265162 | 0.76 | ALOX5AP (0.36) | ALOX5APFEN1GAARAB9ANPC1 | |
| SCHEMBL10221817 | 0.75 | PKM (0.49) | PLCG1CYP11B1PKMGRM5ALDH1A1 | |
| SCHEMBL22551784 | 0.74 | USP8 (0.43) | PLCG1CYP11B1GAARAB9ANPC1 | |
| SCHEMBL2135396 | 0.74 | TSHR (0.34) | ALOX5APFEN1GAARAB9ANPC1 | |
| SCHEMBL11498598 | 0.73 | PDE5A (0.45) | PLCG1ALDH1A1HPGDMAPT | |
| SCHEMBL2133211 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |