Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940947 | 0.80 | RIPK1 (0.52) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL22652306 | 0.78 | CTH (0.40) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL31087129 | 0.78 | ALDH1A1 (0.42) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL1650978 | 0.77 | EGLN1 (0.44) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL7031804 | 0.76 | HTT (0.40) | LMNAHTTALDH1A1MAPTTDP1 | |
| SCHEMBL9775242 | 0.75 | ALDH1A1 (0.44) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL8787301 | 0.75 | EGLN1 (0.43) | CTHEGLN1LMNAALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL27685625 | 0.75 | EGLN1 (0.43) | CTHEGLN1LMNAALDH1A1MAPT | |
| SCHEMBL7036071 | 0.74 | CNR1 (0.44) | LMNAHTTALDH1A1MAPTTDP1 | |
| SCHEMBL6852859 | 0.74 | HTT (0.44) | LMNAHTTALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266713-A | Aryl alkenoic acid derivatives as leukotriene antagonists | MILES INC. (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0410241-B1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1993-10-20 | — | — | EP | disclosed |
| EP-0410241-A1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |