Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852960 | 0.78 | KCNJ1 (0.79) | ALDH1A1KCNJ1SMN1; SMN2MAPTLMNA | |
| SCHEMBL15720704 | 0.77 | KMT2A (0.48) | ALDH1A1KCNJ1SMN1; SMN2LMNAPKM | |
| SCHEMBL6412174 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KCNJ1SMN1; SMN2MAPTLMNA | |
| SCHEMBL5441998 | 0.77 | POLB (0.56) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL11536207 | 0.77 | POLB (0.56) | POLBKDM4E | |
| SCHEMBL11529719 | 0.77 | POLB (0.78) | SMN1; SMN2LMNAPOLBKMT2AKDM4E | |
| SCHEMBL11478965 | 0.77 | POLB (0.56) | ALDH1A1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL519451 | 0.77 | LTA4H (0.71) | ALDH1A1KCNJ1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11539203 | 0.77 | MEN1 (0.66) | ALDH1A1SMN1; SMN2LMNAPOLBKMT2A | |
| SCHEMBL2719675 | 0.76 | HRH3 (0.69) | ALDH1A1KCNJ1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187189-A | S-aminoalkyl-s-arylsulfoximines as antiarrhythmic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |