Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | TXN | P10599 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391803 | 0.82 | KDM4E (0.61) | NFKB1TERTMEN1KMT2AKDM4E | |
| SCHEMBL1391338 | 0.79 | KDM4E (0.61) | NFKB1KDRTERTMEN1KMT2A | |
| SCHEMBL7879059 | 0.76 | CYP1A2 (0.44) | MEN1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL24490505 | 0.75 | FADS1 (0.41) | TERTMEN1KMT2AKDM4EMAPT | |
| SCHEMBL6394544 | 0.75 | KDR (0.67) | NFKB1KDRMEN1KMT2AKDM4E | |
| SCHEMBL9474913 | 0.73 | CRHR1 (0.40) | TERTMEN1KMT2AKDM4EMAPT | |
| SCHEMBL3100845 | 0.72 | NPC1 (0.56) | MEN1KMT2AKDM4EMAPTAPP | |
| SCHEMBL9475606 | 0.72 | KDM4E (0.40) | TERTMEN1KMT2AKDM4EMAPT | |
| SCHEMBL24497026 | 0.72 | EGFR (0.40) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL2804015 | 0.71 | RAB9A (0.41) | MEN1KMT2AKDM4EMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243047-A | Triazole/thiazole amino-s-triazine bonding agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-07 | — | — | US | disclosed |
| US-4978756-A | A 2-MERCAPTO, ALKYLANOYL, ALKENOYL OR ALKDIENOYL AMINO BENZOTHIOZOLE; METALS PROTECTIVE COATING; IMPROVED BONDING OF METALS AND RUBBER; TIRE CORDS | ICI AMERICAS INC. (US) | 1990-12-18 | — | — | US | disclosed |
| EP-0331279-A2 | Compound and use | ZENECA LIMITED (GB) | 1989-09-06 | — | — | EP | disclosed |