Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857412 | 0.87 | CA5A (0.55) | CA5AHPGDSMN1; SMN2GALR3CYP3A4 | |
| SCHEMBL9475577 | 0.84 | HPGD (0.52) | HPGDSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL10662727 | 0.84 | CA5A (0.52) | CA5AHPGDTP53ADORA3ADORA2A | |
| SCHEMBL10666069 | 0.83 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL9475498 | 0.80 | NPC1 (0.59) | HPGDSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL9857903 | 0.79 | CA5A (0.46) | CA5ATSHRMAPTALDH1A1 | |
| SCHEMBL10662709 | 0.79 | CA5A (0.49) | CA5AHPGDSMN1; SMN2CYP1A2TP53 | |
| SCHEMBL9475525 | 0.78 | POLB (0.62) | HPGDSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL11245223 | 0.78 | HPGD (0.80) | HPGDSMN1; SMN2GALR3CYP3A4CYP2C9 | |
| SCHEMBL461525 | 0.74 | HTT (0.47) | CA5AHPGDHTTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007697-A1 | 5-AMINO-1-ALKYL-1H-1,2,3-TRIAZOLE-4-FORMAMIDE COMPOUND, AND PREPARATION AND USE THEREOF | 浙江大学 | 2025-01-09 | — | — | WO | disclosed |
| CN-116854644-A | 5-amino-1-alkyl-1H-1, 2, 3-triazole-4-carboxamide compound, preparation and application thereof | 浙江大学 | 2023-10-10 | — | — | CN | disclosed |
| US-5204353-A | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0288431-B1 | 3H-1,2,3-triazolo[4,5-d]pyrimidines | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |