SCHEMBL9477337

SCHEMBL9477337

CCC(CC)(CC)c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.43
TSHR P16473 1/20 0.43
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
ALDH1A1 P00352 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
CHRM3 P20309 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASR P41180 1/20 0.33
CYP2A6 P11509 2/20 0.32
TRPA1 O75762 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352221 0.78 TSHR (0.41) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL12713575 0.76 ACHE (0.39) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL20318419 0.76 ACHE (0.39) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL11431192 0.76 ACHE (0.39) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL15656197 0.76 TSHR (0.39) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL13462898 0.76 TSHR (0.39) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL20978209 0.75 L3MBTL1 (0.42) TSHRALDH1A1MAPTHTTTAAR1
Water SCHEMBL8529286 0.75 TSHR (0.38) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL2844071 0.75 TSHR (0.38) ACHETSHRGABRA1GABRB2ALDH1A1
SCHEMBL18297346 0.75 TSHR (0.38) ACHETSHRGABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5235115-A Selective ethylation of 2-alkoxy-naphthalene compounds AMOCO CORPORATION (US) 1993-08-10 US disclosed