Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31208447 | 1.00 | TSHR (0.38) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL6683931 | 0.78 | KCNN4 (0.41) | TSHRCHRM3TAAR1 | |
| SCHEMBL27994602 | 0.78 | TAAR1 (0.39) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL4352221 | 0.77 | TSHR (0.41) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL6684003 | 0.77 | RIPK1 (0.37) | TSHRALDH1A1TDP1L3MBTL1CA1 | |
| SCHEMBL4237173 | 0.77 | TSHR (0.45) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL2495517 | 0.77 | TSHR (0.45) | TSHRACHEGABRA1GABRB2CASR | |
| SCHEMBL10627850 | 0.76 | MEN1 (0.37) | TSHRACHEGABRA1GABRB2CASR | |
| Ammonia Solution, Strong SCHEMBL9687521 | 0.75 | MEN1 (0.36) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL9477337 | 0.75 | ACHE (0.43) | TSHRACHEGABRA1GABRB2CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252154-B1 | METHOD FOR MINIMIZING THE CYTOTOXICITY OF THE EFFECTIVE AGENT IN A COMPOSITION THAT IS ADMINISTERED TO A MAMMAL OR GETS INTO CONTACT WITH A MAMMAL | OY GRANULA AB LTD (FI) | 2016-01-27 | — | — | EP | disclosed |
| US-8496974-B2 | Method for preparing a composition comprising a compound mixture and a carrier agent | OY GRANULA AB LTD (FI) | 2013-07-30 | — | — | US | disclosed |
| US-8431170-B2 | Antimicrobial composition with low cytotoxicity | OY GRANULA AB LTD. (FI) | 2013-04-30 | — | — | US | disclosed |
| US-20100129304-A1 | METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| US-20100129302-A1 | ANTIMICROBIAL COMPOSITION WITH LOW CYTOTOXICITY | OY GRANULA AB LTD (FI) | 2010-05-27 | — | — | US | disclosed |
| EP-1732897-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE CONDITIONS | Bayer Pharmaceuticals Corporation (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1714663-A1 | Disinfecting and sanitizing article for hands and skin and hard surfaces | Illinois Tool Works, Inc. (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005097752-A1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE CONDITIONS | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129302-A1 | ANTIMICROBIAL COMPOSITION WITH LOW CYTOTOXICITY | CUTA, LCT, PYCARD | TSHR 4803/4885ACHE 2198/4885GABRA1 4545/4885 |
| US-20100129304-A1 | METHOD FOR PREPARING A COMPOSITION COMPRISING A COMPOUND MIXTURE AND A CARRIER AGENT | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, BAK1, PMAIP1 | TSHR 4698/4885ACHE 3647/4885GABRA1 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.